A study to evaluate exposure to selected smoke constituents when using heated tobacco products

A study to evaluate exposure to selected smoke constituents in healthy adult smokers using heated tobacco products for 5 days under clinical confinement - A study to evaluate exposure to selected smoke constituents in healthy adult smokers using heated tobacco products for 5 days under clinical confinement

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041539

Enrollment

Registered

2021-04-22

Start date

2020-08-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smokers

Interventions

&lt

Smokers&gt

Use of subject&#39

s own brand cigarette for 2 days (clinical confinement)-Use of heated tobacco product A for 5 days (clinical confinement) &lt

Use of subject&#39

s own brand cigarette for 2 days (clinical confinement)-Use of heated tobacco product B for 5 days (clinical confinement) &lt

s own brand cigarette for 2 days (clinical confinement)-Use of heated tobacco product C for 5 days (clinical confinement) &lt

s own brand cigarette for 2 days (clinical confinement)-Use of heated tobacco product D for 5 days (clinical confinement) &lt

s own brand cigarette for 2 days (clinical confinement) -Continued use of subject&#39

s own brand cigarette for 5 days (clinical confinement) &lt

s own brand cigarette for 2 days (clinical confinement) -Abstinence from smoking for 5 Days (clinical confinement)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Subjects who sign the study-specific consent form -Subjects who are confirmed to be in good health from all of the inspection results -Subjects who smoke commercial cigarettes more than one year etc.

Exclusion criteria

Exclusion criteria: -Subjects who have used tobacco products other than commercial cigarettes (i.e. heated tobacco products, hand-rolled cigarettes, cigarillos, cigars, pipes, snuff tobacco, chewing tobacco, etc.) within one week before screening -Pregnant or lactating women or women who may be pregnant -Employed by the tobacco industries, CRO or clinical facility etc.

Design outcomes

Primary

Measure	Time frame
The difference of biomarkers of exposure to selected smoke constituents between the investigational groups	—

Countries

Japan

Contacts

Public ContactChikako Sakaguchi

JAPAN TOBACCO INC. Scientific Regulatoly Affairs, Tobacco Business Headquarters

chikako.sakaguchi@jt.com080-2191-1784

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026