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SMartphone Intervention to LEssen depression/Anxiety and GAIN resilience for cancer patients: SMILE AGAIN project

Optimizing smartphone psychotherapy for depression and anxiety among patients with cancer: multiphase optimization strategy [MOST] by using innovative clinical trial system - Optimizing smartphone psychotherapy for depression and anxiety among patients with cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000041536
Enrollment
352
Registered
2020-11-01
Start date
2021-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer

Interventions

Smartphone Psycho-therapy &lt
Patient Education:PE+Problem Solving
PS+Behavioral Activation
BA+Assertion Training
AT&gt
Smartphone Psycho-therapy(PE+BA+PS+AT) Smartphone Psycho-therapy(PE+PS+BA) Smartphone Psycho-therapy(PE+BA+PS) Smartphone Psycho-therapy(PE+AT+PS) Smartphone Psycho-therapy(PE+PS+AT) Smartphone Psycho

Sponsors

Japan Supportive, Palliative and Psychosocial Oncology Group
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. diagnosis of cancer and awareness of the cancer diagnosis 2. an age of 20 years or older 3. being a smartphone user and able to complete an electronic patient-reported outcome (e-PRO) using an smartphone 4. estimated prognosis is more than six months 5. who are expected to be able to concentrate on intervention for about two months after participation of this study (e.g. who doesn't plan to use cell-killing anticancer drug with strong side effect)

Exclusion criteria

Exclusion criteria: 1. patients who did not understand the Japanese language;2. patients whom attending physicians recognized as inappropriate by psychiatric symptom (e.g. dementia, cognitive impairment and severe depression with suicide ideation) 3. patients who had received cognitive behavioral therapy 4. patients who had received smartphone cognitive behavioral therapy or participated on our previous study

Design outcomes

Primary

MeasureTime frame
the change in Patient Health Questionnaire-9 (PHQ-9) total score from baseline to 8 weeks later

Secondary

MeasureTime frame
the change in Generalized Anxiety Disorder-7 (GAD-7) total score from baseline to 8 weeks later

Countries

Japan

Contacts

Public ContactTatsuo Akechi

Nagoya City University Graduate School of Medical Sciences Department of Psychiatry and Cognitive-Behavioral Medicine

info@smileagain-project.org052-853-8271

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026