A new perioperative glucocorticosteroid replacement therapy for cushing syndrome

A new perioperative glucocorticosteroid replacement therapy for cushing syndrome - A perioperative glucocorticosteroid replacement therapy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041513

Enrollment

Registered

2020-09-01

Start date

2014-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative

Interventions

Hydrocortisone was given during adrenal resection by intravenous injectionon the surgical day.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients who accepted adrenal gland surgery were included in this study.

Exclusion criteria

Exclusion criteria: The patients who had unilateral or bilateral adrenal tumor or nodule but not accepted adrenal gland surgery were excluded in this study.

Design outcomes

Primary

Measure	Time frame
Adrenal insufficiency and steroid withdrawal syndrome were not occurred with all patients. Compared with the concentration of urine cortisol preoperation, it was significantly decreased on the day 7 postoperative. Plasma cortisol concentration was significantly decreased on the day 6 postoperative compared with preoperative. All the patients were followed up to 6 months,plasma cortisol and 24h urine cortisol levels were all normal.	—

Measure

Time frame

Adrenal insufficiency and steroid withdrawal syndrome were not occurred with all patients. Compared with the concentration of urine cortisol preoperation, it was significantly decreased on the day 7 postoperative. Plasma cortisol concentration was significantly decreased on the day 6 postoperative compared with preoperative. All the patients were followed up to 6 months,plasma cortisol and 24h urine cortisol levels were all normal.

—

Countries

Asia(except Japan)

Contacts

Public ContactLiang Wang

Tianjin Medical University General Hospital Deprtment of Urology

aliangws@163.com+8615900209758

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026