Long-term immunodeficiency in septic patients

Consideration of MDSCs in PIICS patients after sepsis shock - COMPASS study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041512

Enrollment

200

Registered

2020-08-21

Start date

2020-08-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

septic shock

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients meeting the criteria for septic shock (Sepsis-3) on admission

Exclusion criteria

Exclusion criteria: (a) pregnant woman (b) HIV infection (c) Malignancies under treatment (d) During chemotherapy or radiation therapy (e) COVID-19 infection (f) Life expectancy at the time of hospitalization is less than three months (g) No request for intensive care

Design outcomes

Primary

Measure	Time frame
Cell counts and ratios of MDSCs at 90th disease day	—

Secondary

Measure	Time frame
(a) mortality (b) Functional evaluation of T cells at 1, 7, 14, 30, 60, and 90th disease days	—

Countries

Japan

Contacts

Public ContactHiromu Naraba

Hitachi General Hospital Department of emergency and critical care medicine

naraba-hok@umin.ac.jp0294-23-1111

Outcome results