The effect of oral probiotics intake after birth on the intestinal microbiota of neonates: a randomized control trial.

The effect of oral probiotics intake after birth on the intestinal microbiota of neonates: a randomized, double-blind, placebo-controlled trial. - The effect of oral probiotics intake after birth on the intestinal microbiota of neonates.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041446

Enrollment

120

Registered

2020-11-01

Start date

2020-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy neonates

Interventions

Probiotics is administered orally to newborns born by a cesarean section at birth, 1 day and 2 day after birth. Placebo is administered orally to newborns born by a cesarean section at birth, 1 day an

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Birth weight of 2000g or more

Exclusion criteria

Exclusion criteria: Twins Pregnant women or newborns transferred to other hospital Newborns with chromosomal anomaly and multiple malformation Newborns whom a manager for this study judged to be inadequate as subjects

Design outcomes

Primary

Measure	Time frame
Gut flora of newborns at 1 and 3 months of age	—

Secondary

Measure	Time frame
Biochemical analysis of stools Urinary metabolite	—

Countries

Japan

Contacts

Public ContactKen Hisata

Juntendo University Faculty of Medicine Department of Pediatrics

ken-hisa@umin.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026