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Evaluation of neoadjuvant therapy by Nematode-NOSE(N-NOSE) using C. elegans

Evaluation of neoadjuvant therapy by Nematode-NOSE(N-NOSE) using C. elegans - Evaluation of NAC by C.elegans

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000041401
Enrollment
167
Registered
2020-08-12
Start date
2020-08-17
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esopahgeal cancer, Gastric cancer, Colorectal cancer, Pancreatic cancer, Breast Cancer

Interventions

None listed

Sponsors

Gifu University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients who undertake neoadjuvant therapy (Chemo, Radiotherapy) at Gifu Univ. 2.Patients more than 20 3.Patients 0ver 70 is applicable in the patient agree to participate in this study, 4.Pattients (Esophageal, gastric, colorectal, pancreatic, breast cancer) who are going to take neoadjuvant therapy (including conversion cases), 5.Any cases taking clinical trials are applicable if this study doesn't dusturb the protocol. 6.Participants (and/or the family) agree to participate in this study.

Exclusion criteria

Exclusion criteria: 1.No indication for neoadjuvant therapy, 2.No agreement by the patient, 3.Active duplicated cancer (synchronous or another cancer less than 5 y. 4.Severe medical complications, 5.Severe systhemic disease and HIV. 6.Pregnant or lactating 7.Severe mental disorder 8.Urinary tract infection

Design outcomes

Primary

MeasureTime frame
ROC-ACU for IRC (chemotaxix index reduction score)

Secondary

MeasureTime frame
1. ROC-AUC for CR by IRS, 2. ROC-AUC accorfing to the following deficitions) 1)IRR1(Preop-Pretreatment), 2)IRR2 (Postop-Preop), 3)IRR4(Post op-Pretreatment, 3.Image, Tumor marker, 4.Patholog, 5. DFS, OS

Countries

Japan

Contacts

Public ContactManabu Futamura

Gifu University, Graduate School of Medicine Department of Surgcal Oncology

mfutamur@gifu-u.ac.jp0582306000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026