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Effects of non-ketogenic low-carbohydrate diet plus interval exercise strategy on cerebral hemodynamics and neurotrophic factor responses: an investigation of physiological regulatory mechanisms (Part 1)

Investigation of the association between dietary nutrients intake and the regulatory factors governing brain health to exercise - Impacts of nutritional state on brain health

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000041393
Enrollment
90
Registered
2020-08-12
Start date
2020-08-12
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The healthy adults who routinely take exercise.

Interventions

None listed

Sponsors

National Taipei University of Nursing and Health Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Subjects who are judged as healthy by self-reported health questionnaire. 2. Subjects who routinely take exercise. 3. Subjects who have no clinical skeletomuscular problems within 12-weeks prior to the study. 4. Subjects who agree to participate in this study with a written informed consent after receiving sufficient explanation relating to this study.

Exclusion criteria

Exclusion criteria: 1. Subjects with respiratory, gastrointestinal, hepatic/gallbladder/pancreatic, cardiovascular and/or mental disease, or who have history of those diseases. 2. Subjects who can't take exercise tolerance by bicycle ergometer. 3. Subjects who have a serious injury or surgical history within 12 weeks prior to this study. 4. Subjects who regularly take drugs, foods for specified health uses, foods with function claims and/or supplements, etc. which would affect this study. 5. Subjects who have cognitive disorder or who have possibility of the disorder. 6. Subjects who are judged as unsuitable for this study by the principal investigator or subinvestigators.

Design outcomes

Primary

MeasureTime frame
Cerebral blood flow/hemodynamic profiles and nutritional state

Secondary

MeasureTime frame
1. Fatigue related scales (VAS, modified Borg scale) 2. Heart rate/cardiovascular responses 3. Energy expenditure during exercise 4. Cognitive and exercise related biochemical examinations of blood

Countries

Asia(except Japan)

Contacts

Public ContactYi-Hung Liao

National Taipei University of Nursing and Health Sciences Department of Exercise and Health Science

yihungliao.henry@gmail.com+886228227101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026