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Optimal dose of normal saline injection to detect correct peripheral venous catheter placement with precordial Doppler ultrasound: a randomized interventional study

Optimal dose of normal saline injection to detect correct peripheral venous catheter placement with precordial Doppler ultrasonography: a randomized interventional study - Optimal dose of normal saline injection to detect correct peripheral venous catheter placement with precordial Doppler ultrasound

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000041330
Enrollment
330
Registered
2020-09-01
Start date
2020-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with elective surgeries in good health conditions

Interventions

1 bolus of normal saline will be administered in the operating rooms. 0.1mL/kg of a normal saline bolus (intervention 1) will be administered via peripheral intravenous lines. 1 bolus of normal salin

Sponsors

Aichi children's general health and medical center, department of Anesthesiology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Elective surgical patients who are planned to be observed at post-anesthesia care unit postoperatively, American society of anesthesiology physical status (ASA) 1 or 2, age is equal of less than 6 years old, weight is between 10 - 20 kg (includes 10 and 20 kg)

Exclusion criteria

Exclusion criteria: Anemia: Hb is less than 10 g/dL On diuretics with a diagnosis of congestive heart failure Abnormal values of electrolytes: Na is less than 135 mEq/L, Na is more than 147 mEq/L, Cl is less than 98 mEq/L, Cl is more than 110 mEq/L, or on treatments

Design outcomes

Primary

MeasureTime frame
Subjective judgement in predefined Doppler sound change (dichotomous outcome), the difference of blood flow velocity on precordial Doppler ultrasonography before and after injecting a bolus of normal saline

Countries

Japan

Contacts

Public ContactTaiki Kojima

Aichi children's general health and medical center Anesthesiology

daiki_kojima@sk00106.achmc.pref.aichi.jp0562-43-0500

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026