Comparison of liver fibrosis by non-invasive MRI Elastography and Shear Wave Elastography in patients with chronic liver disease diagnosed by invasive biopsy and examination of non-alcoholic fatty liver disease by MRI Proton Density Fat Fraction method and frequency-dependent attenuation image

Comparison of liver fibrosis by non-invasive MRI Elastography and Shear Wave Elastography in patients with chronic liver disease diagnosed by invasive biopsy and examination of non-alcoholic fatty liver disease by MRI Proton Density Fat Fraction method and frequency-dependent attenuation image - Comparison of liver fibrosis by non-invasive MRI Elastography and Shear Wave Elastography in patients with chronic liver disease diagnosed by invasive biopsy and examination of non-alcoholic fatty liver disease by MRI Proton Density Fat Fraction method and frequency-dependent attenuation image

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041320

Enrollment

Registered

2020-08-13

Start date

2018-05-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with chronic liver disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with chronic liver diseases such as viral, drug-induced, autoimmune, non-alcoholic fatty liver disease (NAFLD). 2) Patients aged 20 to less than 85

Exclusion criteria

Exclusion criteria: 1) Decompensated cirrhosis. 2) Patients with platelets less than 50,000/ml. 3) Patients with PT less than 40%. 4) Patients with bleeding tendency. 5) Alcoholic liver disease. 6) Patients who need consent from a legal representative. 7) Patients with claustrophobia

Design outcomes

Primary

Measure	Time frame
MRI elastography MRE (shear modulus) Shear Wave Elastography SWE	—

Secondary

Measure	Time frame
Blood test: white blood cell count, white blood cell fraction, hemoglobin, platelets, total protein, albumin, total bilirubin, direct bilirubin, AST, ALT, ALP, GGT, BUN, Cr, ferritin/liver fibrosis markers: Fib4 index, M2BPGi, 4 Type collagen 7s, MRI PDFF method: MRI PDFF value, frequency-dependent attenuation image (ATI method) Liver biopsy: Histological diagnosis of liver biopsy (HAI score)	—

Countries

Japan

Contacts

Public Contactshuko Minami

Public interest incorporated association Kagoshima Kyosaikai Nanpu Hospital Clinical Research Support Office

crc-kenkyu@nanpuh.or.jp0992269111

Outcome results