Attempt to raise the pH of gastric juice during gastric ESD

Attempt to raise the pH of gastric juice during gastric ESD - Attempt to raise the pH of gastric juice during gastric ESD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041299

Enrollment

100

Registered

2020-08-04

Start date

2019-06-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric csncer

Interventions

The day before gastric ESD, vonoprazan 20 mg/day is taken after dinner and ESD is performed.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients diagnosed with early-stage gastric cancer or gastric adenoma by upper gastrointestinal endoscopy, who are indicated for endoscopic treatment and who are not taking vonoprazan or H2A by oral medication are eligible.

Exclusion criteria

Exclusion criteria: Exclude people who are already taking PPIs

Design outcomes

Primary

Measure	Time frame
On the day of ESD, gastric juice is collected and measured for pH before the endoscopic procedure, and an upper gastrointestinal endoscopy is performed the day after the completion of ESD and at 2 months to confirm the size and healing of the ulcer after endoscopic treatment.	—

Countries

Japan

Contacts

Public ContactDaisuke Suto

International University of Health and Welfare Hospital Department of Gastroenterology

daisuto@iuhw.ac.jp0287-39-3060

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026