Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus

Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus - Study on the association between AGEs and sleep apnea syndrome in patients with type 2 diabetes mellitus

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041279

Enrollment

100

Registered

2020-08-02

Start date

2020-08-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetes mellitus

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients with a diagnosis of type 2 diabetes at the time of obtaining consent (2) Patients who were 20 years of age or older at the time of obtaining consent (3) The participant himself or herself is fully informed about the research and agrees in writing. (4) Any gender

Exclusion criteria

Exclusion criteria: (1) Patients using CPAP for the diagnosis of obstructive sleep apnea syndrome (2) After extreme sunburn (3) Serious infections, currently being treated for a carrier cancer (can be included if the patient is in remission and being followed up), serious respiratory disease,serious trauma, serious neurological or autonomic disorders, hyperthyroidism or hypothyroidism(can be included if under treatment and under control) (4) Type 1 diabetes patients (5) Pregnant patients (6) Patients on dialysis (7) Patients with persistent non-sinus arrhythmias (8) Patients with pacemaker implantation (9) Patients taking an alpha-blocker (10) Patients undergoing treatment with steroids (oral or injectable) (11) Patients with craniofacial abnormalities. (12) Other items deemed inappropriate by the physician in charge (13)Patients refused to participate in the study by blanket consent

Design outcomes

Primary

Measure	Time frame
Correlation between skin AF and AHI measured by watch PAT.	—

Secondary

Measure	Time frame
1.Correlation of PSQI, ESS, NoSAS score and No-apnea score with skin AF. 2.Correlation of PSQI, ESS, NoSAS score and No-apnea score with AHI measured by watch PAT. 3.Correlation of carotid artery echocardiography, Endo PAT, ABI, baPWV, CAVI and other macrovascular diseases, body composition analysis, and microvascular diseases with skin AF. 4.Correlation of carotid artery echocardiography, Endo PAT, ABI, baPWV, CAVI and other macrovascular diseases, body composition analysis, and microvascular diseases with AHI measured by watch PAT.	—

Measure

Time frame

1.Correlation of PSQI, ESS, NoSAS score and No-apnea score with skin AF. 2.Correlation of PSQI, ESS, NoSAS score and No-apnea score with AHI measured by watch PAT. 3.Correlation of carotid artery echocardiography, Endo PAT, ABI, baPWV, CAVI and other macrovascular diseases, body composition analysis, and microvascular diseases with skin AF. 4.Correlation of carotid artery echocardiography, Endo PAT, ABI, baPWV, CAVI and other macrovascular diseases, body composition analysis, and microvascular diseases with AHI measured by watch PAT.

—

Countries

Japan

Contacts

Public ContactMasahiro Ichikawa

Yokohama City University Medical Center Department of endocrinology & metabolism

t196009c@yokohama-cu.ac.jp045-261-5656

Outcome results