Diagnostic efficacy and safety of transesophageal endoscopic ultrasound with bronchoscope-guided fine needle aspiration (EUS-B-FNA) for the patients with lung cancer with respiratory failure

Diagnostic efficacy and safety of transesophageal endoscopic ultrasound with bronchoscope-guided fine needle aspiration (EUS-B-FNA) for the patients with lung cancer with respiratory failure - Diagnostic efficacy and safety of transesophageal endoscopic ultrasound with bronchoscope-guided fine needle aspiration (EUS-B-FNA) for the patients with lung cancer with respiratory failure

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041235

Enrollment

Registered

2020-07-28

Start date

2020-07-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The patients with suspicion of lung cacner on radiological examinations. 2. Patiants who have a lesion adjacent to esophagus which is accessible by EUS-B-FNA. 3. Patients who need oxygen therapy to maintain oxygen saturation (90%), whose condition make it impossible or difficult to perform bronchoscopy because of respiratory comorbidity, or who have poor ECOG-PS (2 or more).

Exclusion criteria

Exclusion criteria: 1. Patients with esophageal varices or coagulation disorder. 2. Pregnant woman.

Design outcomes

Primary

Measure	Time frame
Diagnostic yeild and safety of EUS-B-FNA.	—

Secondary

Measure	Time frame
Ratio of evaluable samples by the PD-L1 immunohistochemistry. Ratio of evaluable samples of oncogene mutation status (EGFR, ROS1, ALK, and BRAF). Overall survival. Overall survival stratified by existence of driver oncogene or tumor PD-L1 expression.	—

Countries

Japan

Contacts

Public ContactYukihiro Umeda

University of Fukui Third department of internal medicine

umeda@u-fukui.ac.jp0776613111

Outcome results