healthy volunteer
Conditions
Interventions
injection of [18F]SMBT-1
Sponsors
Tohoku University Cyclotron and Radioisotope Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Informed consent by the participant or by the substitue (native Japanese) (2) Ages: 20 to 70 years old (3) Those who can tolerate relatively long PET examination (up to 5 hours)
Exclusion criteria
Exclusion criteria: AN group (1) Pregnancy and breast feeding, and within 28 days after delivery (2) Severe allergic reactions to drugs and foods (3) Habitual smoking (including those who have smoked within 1 year) (4) Taboo conditions for MRI examinations (cardiac pacemaker, intracorpoporial metals, etc. to be checked with questionnaire in advance) (5) Sever deformity or deficienty of organs due to accidents, operations, and developmental problems. (6) Systemic circulatory and metabolic disorders as well as organ dysfuctions, such as diabetes melitus, hypertension, endocrinological disorders, congestive heart failure, angina petoris, severe renal dysfunctions (7) Being diagnosed or treated for malignant diseases within 1 year (8) Any sociomedial conditions, which may make the participation to this study difficult
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Standardized Uptake Ratio (SUV) after injection of [18F]SMBT-1 in each organ | — |
Secondary
| Measure | Time frame |
|---|---|
| Standardized Uptake Ratio (SUV) after injection of [18F]SMBT-1 in each organ and its time course information, as well as an estimated value of radiation exposure in each organ | — |
Countries
Japan
Contacts
Public ContactKazuko Takeda
Tohoku University Cyclotron and Radioisotope Center
Outcome results
None listed