Observation of the effects of inflammatory response caused by surgery on the body fluid

Quantitative analysis of the surgery-induced inflammatory response on the body fluid distribution. - Inflammatory response and body fluid

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041150

Enrollment

Registered

2020-07-27

Start date

2020-07-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major abdominal surgery

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing elective major non-cardiac surgery Estimated surgical duration over 6 hours Postoperative ICU admission

Exclusion criteria

Exclusion criteria: Preoperative systemic inflammation Preoperative chronic kidney disease

Design outcomes

Primary

Measure	Time frame
)Correlation analysis between plasma presepsin, syndecan-1 and body composition during surgery and first postoperative day	—

Secondary

Measure	Time frame
(1)Correlation analysis between plasma presepsin, syndecan-1 and body weight change during surgery and first postoperative day (2) Correlation analysis between plasma presepsin, syndecan-1 and urinary NGAL-1 concentration during surgery and first postoperative day	—

Countries

Japan

Contacts

Public ContactYuki Kawamura

Toho University Ohashi Medical Center Institutional review board

ohashi.rinri@ext.toho-u.ac.jp03-3468-1251

Outcome results