Predicting effective and safe fluid removal by furosemide bolus administration in critically ill neonates and infants

Predicting effective and safe fluid removal by furosemide bolus administration in critically ill neonates and infants - Predicting effective and safe fluid removal by furosemide bolus administration in critically ill neonates and infants

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000041048

Enrollment

Registered

2020-07-09

Start date

2018-03-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-cardiac critically ill neonates and infants

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with an arterial line and urinary catheter who were administrated furosemide bolus were enrolled.

Exclusion criteria

Exclusion criteria: Furosemide boluses in patients meeting any of the following criteria were excluded: 1) patients undergoing any type of dialysis; 2) history of any type of congenital heart disease; 3) presence of complications known to affect urinary output, such as diabetes insipidus or severe hyperglycemia; 4) use of other diuretics (including furosemide) within 6 h preceding the index furosemide bolus; or 5) use of any kind of extra-corporeal circulation.

Design outcomes

Primary

Measure	Time frame
Furosemide bolus was classified as effective and safe if urine output within 2 h after administration exceeded 10 mL/kg/h and systolic blood pressure did not drop below 60 mmHg.	—

Countries

Japan

Contacts

Public ContactNatsuhiro Yamamoto

Yokohama City University Graduate School of Medicine Department of Anesthesiology and Critical Care Medicine

natsuyamamo@gmail.com0457872918

Outcome results