Evaluation of Reliability of Post-Tetanic Motor-Evoked Potential Monitoring Under Desflurane Anesthesia

Evaluation of Reliability of Post-Tetanic Motor-Evoked Potential Monitoring Under Desflurane Anesthesia - Post-Tetanic Motor-Evoked Potential Monitoring Under Desflurane Anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000041003

Enrollment

Registered

2020-07-05

Start date

2018-08-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar diseases

Interventions

Desflurane post-tetanic stimulation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Lumbar diseases patients over 20 years old

Exclusion criteria

Exclusion criteria: emergency cases, trauma cases, with CSM cases, infection cases, epilepsia cases, pace maker cases, who rejected to join the study

Design outcomes

Primary

Measure	Time frame
Both c-MEP and p-MEP monitoring were performed throughout the operation in each patient. For recording c-MEPs, transcranial electrical train of five pulses stimulation with an interstimulus interval of 1 second was performed and CMAP were bilaterally recorded from abductor pollicis brevis, abductor hallucis, tibialis anterior, and soleus muscles. For recording p-MEPs, tetanic stimulation (50 Hz, 50 mA, 5 sec) was applied to the left median nerve and bilateral tibial nerves 1 second before transcranial stimulation and CMAPs were recorded from the same muscles. The false positive, false negative, and accuracy of MEP monitoring in the detection of change in motor function were compared between p-MEP and c-MEP.	—

Measure

Time frame

Both c-MEP and p-MEP monitoring were performed throughout the operation in each patient. For recording c-MEPs, transcranial electrical train of five pulses stimulation with an interstimulus interval of 1 second was performed and CMAP were bilaterally recorded from abductor pollicis brevis, abductor hallucis, tibialis anterior, and soleus muscles. For recording p-MEPs, tetanic stimulation (50 Hz, 50 mA, 5 sec) was applied to the left median nerve and bilateral tibial nerves 1 second before transcranial stimulation and CMAPs were recorded from the same muscles. The false positive, false negative, and accuracy of MEP monitoring in the detection of change in motor function were compared between p-MEP and c-MEP.

—

Countries

Japan

Contacts

Public ContactSachiko Kawasaki

Nara Medical University Orthopedic surgery

sachi-kawa@naramed-u.ac.jp0744-22-3051

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026