Advanced endoscopic imaging to diagnose advanced histology of small colorectal polyps: a multicenter prospective observational trial

Advanced endoscopic imaging to diagnose advanced histology of small colorectal polyps: a multicenter prospective observational trial - ADVENTURE trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040974

Enrollment

1100

Registered

2020-07-01

Start date

2020-07-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal polyp

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)Patients for elective colonoscopy (2)Patients who can be obtained informed consent

Exclusion criteria

Exclusion criteria: (1)Patients with advanced colorectal cancers (2)Patients with hemorrhagic disorders (3)FAP, Polyposis, Lynch syndrome (4)Patients with hemorrhagic tendency (5)Patients with anti-thrombotic agents (6)Pregnancy (7)Disqualified patients with other reasons

Design outcomes

Primary

Measure	Time frame
Negative predictive value of diagnosis of advanced histology using WLI+NBI+IC	—

Secondary

Measure	Time frame
(1)Sensitivity, Specificity and positive predictive value of diagnosis of advanced histology using WLI+NBI+IC (2)Diagnostic parameter of other combinations of diagnosis of advanced histology (3)Rate of non-cold snare polypectomy for advanced histology (4)Complications(perforation, bleeding, GI symptoms) (5)Rate of surgical margin negative (6)Rate of including MM and SM	—

Countries

Japan

Contacts

Public ContactKinichi Hotta

Shizuoka Cancer Center Division of Endoscopy

k.hotta@scchr.jp055-989-5222

Outcome results