Development of a novel method for prognostic prediction and precision medicine in pancreatic adenocarcinoma using fine-needle biopsy tissues collected from intraoperative specimen

Development of a novel method for prognostic prediction and precision medicine in pancreatic adenocarcinoma using fine-needle biopsy tissues collected from intraoperative specimen: A two-center, double-blind, randomly allocated comparative study - Development of a novel method for prognostic prediction and precision medicine in pancreatic adenocarcinoma using fine-needle biopsy tissues collected from intraoperative specimen

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040972

Enrollment

Registered

2020-07-03

Start date

2020-07-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic cancer

Interventions

Quantitative measurement of Smad4 protein FNB immunostaining pathology judgement

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Pantients with pancreatic cancer who undergo surgery including pancreaticoduodenectomy, distal pancreatectomy, and total pancreatectomy, afte pancreatic cancer is suspected by objective finding (e.g., US, Abdominal CT, Abdminal MRI) 2. more than 20 years old 3. Patients provided written informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Inoperable case (e.g., caricninomatosa was found out) during surgery. 2. Patient with mental disease and it is difficult to participate in study. 3. Patints who refuse to participate in this study.

Design outcomes

Primary

Measure	Time frame
Evaluation of the correlation between immunohistochemistry-scores and novel quantitative analysis for Smad4.	—

Countries

Japan

Contacts

Public ContactMasafumi Chiba

The Jikei University School of Medicine Department of Endoscopy

ccl09720@gmail.com03-3433-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026