Cerebral lateralization of ankle joint position sense in healthy left- and right-side dominant adults studied by functional magnetic resonance imaging

Cerebral lateralization of ankle joint position sense in healthy left- and right-side dominant adults studied by functional magnetic resonance imaging - MRIJPS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040959

Enrollment

Registered

2020-08-01

Start date

2021-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy people

Interventions

Unilateral and bilateral active motor tasks: Ipsilateral matching task: Contralateral matching task:

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy participants more than 20 years old left- and right-side dominant

Exclusion criteria

Exclusion criteria: history of neurological or orthopaedic disorders other diseases injury claustrophobia anything against performing MRI

Design outcomes

Primary

Measure	Time frame
We will adopt a conventional two-level approach for a block-design fMRI data using SPM12. A voxel-by-voxel multiple regression analysis will be conducted for the first-level within-subject (fixed effects) model. We will construct for each subject a model of expected signal changes involving the four conditions; 2 measurement conditions(ipsilateral/contralateral) by 2 foot-laterality conditions(right/left).	—

Measure

Time frame

We will adopt a conventional two-level approach for a block-design fMRI data using SPM12. A voxel-by-voxel multiple regression analysis will be conducted for the first-level within-subject (fixed effects) model. We will construct for each subject a model of expected signal changes involving the four conditions; 2 measurement conditions(ipsilateral/contralateral) by 2 foot-laterality conditions(right/left).

—

Secondary

Measure	Time frame
Any deviation from the target position, discounting direction, was defined as the absolute position error: 1) E absolute = ABS(Xparticipant - Xtarget) For constant error, the difference between reproduced and actual target angle was used, considering the direction of the error: 2) E constant = ( Xparticipant - Xtarget ) 3) E variable: The variable error was calculated as the overall standard deviation (SD) of constant error from 14 trials, irrespective of the target range:	—

Measure

Time frame

Any deviation from the target position, discounting direction, was defined as the absolute position error: 1) E absolute = ABS(Xparticipant - Xtarget) For constant error, the difference between reproduced and actual target angle was used, considering the direction of the error: 2) E constant = ( Xparticipant - Xtarget ) 3) E variable: The variable error was calculated as the overall standard deviation (SD) of constant error from 14 trials, irrespective of the target range:

—

Countries

Japan

Contacts

Public ContactRyoichi Nagatomi

Tohoku University Division of Biomedical Engineering for Health & Welfare

nagatomi@med.tohoku.ac.jp8122-717-8588

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026