A prospective cohort study for evaluating the short-term outcomes of laparoscopic gastrectomy for advanced gastric cancer with preoperative chemotherapy

A prospective cohort study for evaluating the short-term outcomes of laparoscopic gastrectomy for advanced gastric cancer with preoperative chemotherapy - A prospective cohort study of laparoscopic gastrectomy for advanced gastric cancer with preoperative chemotherapy

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040954

Enrollment

Registered

2020-07-01

Start date

2020-05-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced gastric cancer with preoperative chemotherapy

Interventions

Laparoscopic gastrectomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Histologically proven gastric adenocarcinoma 2) Clinical Stage III or Stage IV gastric cancer curably treated with total, proximal, or distal gastrectomy after preoperative chemotherapy 3) ECOG performance status of 0 or 1 4) Informed consent is obtained

Exclusion criteria

Exclusion criteria: 1) With active double or multiple cancers 2) Severe complications 3) With active infection 4) Past history of severe hypersensitivity to drugs 5) Patients judged inappropriate for the study by the physicians

Design outcomes

Primary

Measure	Time frame
Incidence of anastomotic leakage greater than Grade 2 and pancreatic fistula greater than Grade 3 according to Clavien-Dindo classification	—

Secondary

Measure	Time frame
1. Rate of curative resection (R0, R1), 2. Overall survival, 3. Relapse-free survival, 4. Completion rate of laparoscopic surgery, 5. Rate of conversion to open surgery, 6. Intraoperative complications, 7. Postoperative complications, 8. Surgery-related death within 30 days, 9. In-hospital mortality, 10. Postoperative course, 11. Patterns of recurrence	—

Countries

Japan

Contacts

Public ContactTsuyoshi Etoh

Oita University Faculty of Medicine Department of Gastroenterological and Pediatric Surgery

teto@oita-u.ac.jp097-586-5843

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026