The research for the relationship between dry eye with corneal neuropathic pain and galectin-3 concentration in tear

The research for the relationship between dry eye with corneal neuropathic pain and galectin-3 concentration in tear - The research for the relationship between dry eye with corneal neuropathic pain and galectin-3 concentration in tear

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040952

Enrollment

Registered

2020-07-07

Start date

2020-07-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Dry eye group 1. Those who plan to go to an ophthalmology outpatient in Keio University Hospital to be performed dry eye examination and medical treatment 2. Those who are 30 years old or older and have voluntarily agreed to their documents 3. No history of keratoconjunctival surgery within the past year 4. Dry eye patients diagnosed as dry eye that meet the dry eye diagnostic criteria (Attachment) Dry eye diagnostic criteria 2016 version (Dry eye study group) 1) Subjective symptoms of dry eye such as eye discomfort and abnormal visual function 2) Tear break up time (BUT) is 5 seconds or less A positive finding for all parameters was considered grounds for a positive diagnosis of dry eye. Normal group 1.Those who wish to participate in the research as volunteers who are visiting the ophthalmology clinic 2. Those who are 30 years old or older and have voluntarily agreed to their documents 3. No history of keratoconjunctival surgery within the past year 4. Meets the conditions 1)-3) below parameters 1) There are no subjective symptoms of dry eye such as eye discomfort or visual dysfunction 2) BUT is 6 seconds or more 3) No keratoconjunctival epithelial disorder

Exclusion criteria

Exclusion criteria: Exclude people who meet any of the following conditions from both dry eye group and control group 1. Those who do not agree with the ophthalmic examination 2. Those who do not consent to tear collection 3. Those who have a history of keratoconjunctival surgery within the past year

Design outcomes

Primary

Measure	Time frame
the galectin-3 concentration in tears	—

Countries

Japan

Contacts

Public ContactYuichi Uchino

Keio University Hospital Department of Ophthalmology

uchino.z2@keio.jp03-3353-1211

Outcome results