Health-related quality of life in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors and immunotherapy: An observational study (PROmRCC study)

Health-related quality of life in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors and immunotherapy: An observational study (PROmRCC study) - Health-related quality of life in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors and immunotherapy: An observational study (PROmRCC study)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040922

Enrollment

Registered

2020-06-30

Start date

2018-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal cell carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria was mRCC patients (1) who had the IMDC intermediate- or poor-risk disease, (2) who were able to answer QoL questionnaire, and (3) without active autoimmune disease.

Exclusion criteria

Exclusion criteria: Exclusion criteria were mRCC patients (1) who had the IMDC favorable-risk disease, (2) who were not able to answer QoL questionnaire, and (3) who were not feasible for immunotherapy.

Design outcomes

Primary

Measure	Time frame
The primary objective was to compare the HRQoL difference between the baseline and three months after treatment.	—

Secondary

Measure	Time frame
The secondary objective was to compare the HRQoL between patients with and without severe (grade 3 or higher) irAEs. The exploratory objective was to compare the HRQoL between patients treated with immunotherapy as well as TKIs three months after treatment.	—

Countries

Japan

Contacts

Public ContactShingo Hatakeyama

Dept. of Urology, Hirosaki University Graduate School of Medicine Urology

shingorilla2@gmail.com0172395091

Outcome results