Effect of Dexmedetomidine versus Remifentanil on early recovery from anesthesia and Morphine consumption in laparoscopic sleeve gastrectomy obese patients

Impact of intraoperative use of Dexmedetomidine versus Remifentanil on postoperative enhanced recovery and Morphine consumption in obese patients for laparoscopic sleeve gastrectomy - Impact of intraoperative use of dexmedetomidine versus remifentanil on the enhanced recovery characteristics following laparoscopic sleeve gastrectomy. A clinical observational pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040880

Enrollment

Registered

2020-06-24

Start date

2019-12-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

No any

Interventions

Dexmedetomidine 200 micrograms (mics) diluted in 50 milliliters (ml) normal saline. The final concentration will be 4 mics/ml. Dose 0.2- 0.7 mics/kg/hour under general anesthesia for the duration of

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1- ASA I, II 2- Age 18-60 years 3- Either gender 4- Obese patients (BMI >35 for laparoscopic sleeve gastrectomy)

Exclusion criteria

Exclusion criteria: 1- Uncontrolled Hypertension 2- Age below 18 and older than 60 3- Non-Obese patients (BMI< 35) 4- Heart block > Ist degree 5- Allergic to morphine, alpha-2 agonist 5- Clinically significant neurological, cardiovascular, renal hepatic disease 6- History of drug abuse or chronic opioid use

Design outcomes

Primary

Measure	Time frame
To assess the effect of Dexmedetomidine and Remifentanil on postoperative pain in obese patients scheduled for laparoscopic sleeve gastrectomy under general anesthesia	—

Secondary

Measure	Time frame
To assess the effect of Dexmedetomidine and Remifentanil on postoperative quality of recovery from general anesthesia (i.e. pain, hemodynamics, sedation, agitation, shivering, postoperative nausea & vomiting, length of hospital stay) and Morphine consumption in obese patients scheduled for laparoscopic sleeve gastrectomy.	—

Countries

Asia(except Japan)

Contacts

Public ContactAbdul Sattar Narejo

King Saud University Medical City Anesthesia

narejo27@hotmail.com00966556314525

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026