Type 2 diabetes
Conditions
Interventions
None listed
Sponsors
Yokohama City University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients with type 2 diabetes who were newly prescribed metformin from January 1, 2008 to November 30, 2019 and can be followed by a 24-week observation period(January 1, 2008-May 20, 2020). 2)Patients who have not stopped/changed/added hypoglycemic agents other than metformin during the 24-week observation period(Regarding insulin, the number of units can be changed and canceled). 3)Patients who have not changed or discontinued other antidiabetic drugs at the timing of introducing metformin.
Exclusion criteria
Exclusion criteria: 1)Patients with type 1 diabetes or secondary diabetes. 2)Patients whose other diabetes drugs are changed, increased, or discontinued at the same time as the start of metformin administration. 3) Patients who are changing diabetes drugs other than metformin (including changing the dose) during the 24-week observation period (changes in the number of insulin units can be incorporated). 4) Patients who are judged to have extremely poor medication compliance based on medical records. 5) Patients with steroid (oral/injection) treatment. 6) Patients with cancer (can be included if they are in follow-up during remission). 7) Patients who were hospitalized during the observation period. 8) Patients with severe infections and trauma. 9) Patients who are judged to be inappropriate as a subject by the doctor's judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in HbA1c decrease due to differences in metformin introduction timing (1st, 2nd, 3rd, 4th and later). | — |
Secondary
| Measure | Time frame |
|---|---|
| We compare the changes in body weight, biochemical examination, and incidence of adverse events at the time of introduction and at 24 weeks with the difference in the timing of Metformin introduction. | — |
Countries
Japan
Contacts
Public ContactMARINA HARADA
Yokohama City University Medical Center Department of Endocrinology and Diabetes
Outcome results
None listed