bone metastases
Conditions
Interventions
Arterial embolization with a spherical embolic material is performed for painful bone metastases.
Sponsors
Japan Interventional Radiology in Oncology Study Group (JIVROSG)
Japan Supportive, Palliative and Psychosocial Oncology Group(J-SUPPORT)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Diagnosed as painful bone metastases 2)Strongest pain site matches the bone metastasis site 3)No spinal cord compression in the bone metastasis site 4)The patient has pain described over 5 in Numerical Rating Scale. 5)Patient has received some form of analgesic medication for pain relief. 6)Radiation therapy (RT) has not been performed on the site of arterial embolization within 2 months. 7)The patuient has not been started new chemotherapy or 8)Originated cancer is not limited. 9)promising over 1 month alive after treatment 10)eGFR is over 30 ml/min/1.73m2 11)PT-INR is over 1.5 and Platelet count is over 50000/dl. 12)over 20 years old 13)Signed a consent form
Exclusion criteria
Exclusion criteria: 1)Difficult to hold rest position 2)The patient could not describe pain by Numeric Rating Scale. 3)Preexisting disorders of being allergic to iodinated contrast material 4)Cannot stop anticoagulants and antithrombotic drugs. 5)Qualified ineligible patients being this clinical trial by responsible doctor
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) pain relief at 72 hours after arterial embolization(TAE) 2) adverse events related to TAE 2 weeks after TAE | — |
Countries
Japan
Contacts
Public ContactYasunori Arai
National Cancer Center Hospital East Department of Diagnostic Radiology
Outcome results
None listed