Healthy adults
Conditions
Interventions
Intake test food (2g/day for matcha) for twelve weeks
Intake placebo for twelve weeks
Sponsors
RIKEN
ITO EN, Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Individual who has received sufficient explanation about purpose and content of research, and consenting ability, and who volunteers with his/her free intent and gives written informed consent. 2) Healthy adults between the ages of 40 and under 60 at the time of informed consent.
Exclusion criteria
Exclusion criteria: 1) Subject who uses life support device inside or outside the body 2) Subject with a metallic foreign body inside 3) Subjects using orthodontic metal bridges 4) Subjects using tattoos, eye lines, fashion contact lenses 5) Subjects who were engaged in the metalworking industry 6) Subjects with mental/neurotic attacks or claustrophobia 7) Subjects with impaired hearing, vocalization, or grip strength 8) Subjects with disorders in body temperature regulation and sweating 9) Subjects who have been previously pointed out to have arrhythmia by physical examination. 10) Subjects with an MMSE score of 24 or less. 11) Subjects who cannot perform a computer-based cognitive function test satisfactorily. 12) Subjects who are inadequate for enrollment judged by the responsible physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of brain structure and task-related brain activity before and 12 weeks after starting test food intake | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of cognitive function (Cognitrax, CogEvo-Ri), autonomic nervous function, questionnaires (BDI-II, STAI, NEO-FFI) and daily mood survey (KOKORO scale) before and 12 weeks after starting test food intake | — |
Countries
Japan
Contacts
Public ContactAkihiro Sasaki
RIKEN Center for Biosystems Dynamics Research Laboratory for Pathophysiological and Health Science
Outcome results
None listed