Histological Evaluation of Atrial Fibrillation Substrate on Atrial Septum Biopsy

Histological Evaluation of Atrial Fibrillation Substrate on Atrial Septum Biopsy - HEAL-AF Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040781

Enrollment

100

Registered

2020-06-16

Start date

2020-06-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing catheter ablation for atrial fibrillation and/or left atrial macroreentrant atrial tachycardia Patients undergoing trans-esophageal echocardiography before ablation procedure Patient undergoing atrial fibrillation ablation under general anesthesia or deep sedation Patients undergoing bipolar voltage mapping in the atria during ablation procedure

Exclusion criteria

Exclusion criteria: Pregnant woman Patients in whom thrombus was identified in the left atrium Patients in whom trans-esophageal echocardiography would be impossible Patients with a history of open-heart surgery

Design outcomes

Primary

Measure	Time frame
Relationship between atrial histology and recurrence rate at 3 years after catheter ablation for atrial fibrillation	—

Secondary

Measure	Time frame
Relationship between histological findings and electrophysiological data Relationship between atrial histology and cardiovascular event rate at 3 years after catheter ablation for atrial fibrillation	—

Countries

Japan

Contacts

Public ContactTAKANORI YAMAGUCHI

Saga University Hospital Cardiovascular Medicine

takanori@cc.saga-u.ac.jp0952-34-2443

Outcome results