A healthy adult
Conditions
Interventions
Intervention is 3 days. On each day, a subject washes the mouth using by 180 ml alcohol beverage of different 3 concentration including 0.1 g/kg of body weight, 0.3 g/kg of BW or 0.5 g/kg of BW ethano
Sponsors
Yamaguchi University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: *20<= years-old *Male and Female *A person who has ever drunken a unit of alcohol. *A person who is standard weight (=>18.5 and <25) based on BMI (body mass index) *A person who is provided sufficient explanations about this study and consented to it in writing by his own free will
Exclusion criteria
Exclusion criteria: *a person who has ever had any allergy symptoms by drinking alcohol beverage *a person who has any airway diseases or liver diseases *a person who is probably pregnant or is during pregnancy *a person who is during the lactation *an inappropriate person for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in breath alcohol and acetaldehyde concentrations after mouthwashing with several kinds of alcohol | — |
Secondary
| Measure | Time frame |
|---|---|
| Alcohol sensitivity by alcohol patch test and ADH1B/ALDH2 genotype based on PCR method using oral mucosa | — |
Countries
Japan
Contacts
Public ContactAyako HIMEMIYA-HAKUCHO
Graduate School of Medicine, Yamaguchi University Department of Legal Medicine
Outcome results
None listed