Association Between Ghrelin and Butyrylcholinesterase in Patients With Acute Decompensated Heart Failure: A Cross-sectional Study

Association Between Ghrelin and Butyrylcholinesterase in Patients With Acute Decompensated Heart Failure: A Cross-sectional Study - Association Between Ghrelin and Butyrylcholinesterase in Patients With Acute Decompensated Heart Failure: A Cross-sectional Study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040647

Enrollment

Registered

2020-06-04

Start date

2020-06-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute heart failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who received sufficient explanation, understood it and gave written consent based on their free will, before participating in this study (The consent from their parents or legal guardians is needed for the patients with dementia.)

Exclusion criteria

Exclusion criteria: Patients with liver disorder Patients with past history of removal of stomach Patients who is taking rivastigmine or rikkunshito Patients with anorexia or severe obesity (BMI>35) Patients with endocrine disease

Design outcomes

Primary

Measure	Time frame
Association between plasma ghrelin level and serum butyrylcholinesterase level	—

Secondary

Measure	Time frame
1) Vital signs: blood pressure, heart rate, body weight 2) Blood biomarkers: Albumin, prealbumin, T-chol, LDL-chol, HDL-chol, TG, BNP, NT-proBNP, hs-tropI, high sensitive CRP 3) Transthoracic echocardiography: LVEF, LVDd/Ds, E/e', LAD, LVEDV, LVESV, LV mass, TAPSE, RVEF, LA volume 4) Cardiac MIBG imaging: H/M MIBG uptake ratio on the delayed images, washout rate of cardiac MIBG 5) Body composition (bioimpedance method) 6) Electrocardiogram 7) Appetite score	—

Measure

Time frame

1) Vital signs: blood pressure, heart rate, body weight 2) Blood biomarkers: Albumin, prealbumin, T-chol, LDL-chol, HDL-chol, TG, BNP, NT-proBNP, hs-tropI, high sensitive CRP 3) Transthoracic echocardiography: LVEF, LVDd/Ds, E/e', LAD, LVEDV, LVESV, LV mass, TAPSE, RVEF, LA volume 4) Cardiac MIBG imaging: H/M MIBG uptake ratio on the delayed images, washout rate of cardiac MIBG 5) Body composition (bioimpedance method) 6) Electrocardiogram 7) Appetite score

—

Countries

Japan

Contacts

Public ContactMasahiro Seo

Osaka General Medical Center Department of Cardiology

roland-dyens@hotmail.co.jp09036233037

Outcome results