Assessment of neointimal coverage using two different imaging modalities at 2-week and 6-month after ultrathin vs thin strut drug-eluting stent implantation in coronary artery disease patients with ST elevation myocardial infarction -high-resolution angioscopy and OCT study-

Assessment of neointimal coverage using two different imaging modalities at 2-week and 6-month after ultrathin vs thin strut drug-eluting stent implantation in coronary artery disease patients with ST elevation myocardial infarction -high-resolution angioscopy and OCT study- - NAGAKUTE-CASTLE study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040642

Enrollment

110

Registered

2020-07-01

Start date

2020-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction

Interventions

Orsiro stent Xience stent

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Patients with st-elevation myocardial infarction less than 12 hours after onset (Orsiro group: 55 cases, XIENCE group: 55 cases) (2) Patients who can be followed up in all clinical situations (3) Patients who can be observed by angiography, OCT/OFDI and angioscopy 2 weeks after PCI (4) Patients who can be observed by angiography, OCT/OFDI 6 months after surgery (5) Patients with medical indication of PCI

Exclusion criteria

Exclusion criteria: (1) Patients who cannot obtain written consent after oral consent by the patient or his/her legal representative (2) Patients with cardiogenic shock (3) Hemodialysis patients (4) Left main lesion / Bifurcation lesion requiring two stents / In-stent restenosis lesion (5) The target lesion is in the arterial bypass graft or saphenous vein bypass graft, or distal to the graft anastomosis site (6) Patients who are contraindicated for antiplatelet therapy or anticoagulant therapy (7) Patients who have difficulty in proper drug therapy (8) Patients who have a contraindication to contrast agents or have allergies to contrast agents (9) Patients scheduled for cardiac surgery within 6 months (10) Patients who have participated in another study and have not completed the observation period in that study (11) Patients who are judged to be unfavorable for participation in this study by the investigator and investigator

Design outcomes

Primary

Measure	Time frame
Neointimal coverage rate at 2-week after stent implantation	—

Countries

Japan

Contacts

Public ContactHirohiko Ando

Aichi Medical University Cardiology

anhiro@aichi-med-u.ac.jp0561-62-3311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026