Measurement of the standard value of the elderly to determine the clinical significance of blood substance P level as an objective evaluation index for the prediction of aspiration due to glottal insufficiency

Measurement of the standard value of the elderly to determine the clinical significance of blood substance P level as an objective evaluation index for the prediction of aspiration due to glottal insufficiency - Average value of substance P in the elderly

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040627

Enrollment

Registered

2020-06-11

Start date

2020-06-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy elderly

Interventions

Venous blood sample

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Men and women over the age of 65 2. Those who come to our hospital as an otolaryngology outpatient with normal phonation and swallowing 3. Those who do not have glottal insufficiency during phonation due to vocal cord atrophy on laryngoscopy 4. Those who do not have paralysis in the vocal cords on either side of the larynx and have no other organic functional disorder or disease 5. Those with a maximum phonation time (MPT) of 15 seconds or more 6. Paticipants who match above and agree to cooperate the research

Exclusion criteria

Exclusion criteria: 1. Those who do not understand Japanese 2. Those who are targeted for treatment in the ENT department, those who are taking ACE inhibitors for other treatments 3. MPT less than 15 seconds 4. Persons admitted by each institution doctor as an indication for vocal self-training

Design outcomes

Primary

Measure	Time frame
plasma Substance P value in healthy elderly	—

Countries

Japan

Contacts

Public ContactKoichi Tsunoda

National Hospital Organization National Tokyo Medical Center Artificial Organs and Medical Creations/Otolaryngology

tsunodakoichi@kankakuki.go.jp0334110111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026