Skip to content

Involvement of cervical muscle lesions and autonomic nervous system in treatment-resistant depression

Involvement of cervical muscle lesions and autonomic nervous system in treatment-resistant depression - Involvement of cervical muscle lesions and autonomic nervous system in treatment-resistant depression: Treatment-resistant depression (TRD)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000040590
Enrollment
2000
Registered
2020-06-30
Start date
2007-05-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To clarify the involvement of cervical muscle lesions as well as the autonomic nervous system in patients with treatment-resistant depression

Interventions

Sponsors

There is no outside sponsor associated with this study.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) TRD patients over the age of 10, who visited our institutions from May 2006 through April 2020. 2) Resistant to outpatient care 3) Patients who were hospitalized for 5 to 120 days were enrolled.

Exclusion criteria

Exclusion criteria: 1) Diagnosed to have specific diseases in other organs after admission 2) Underwent surgeries of the cervical spine 3) Received other pharmacological or non-pharmacological treatments in addition to the physical therapies at their insistence 4) Quit the physical therapies due to adverse events that were judged to be therapy-related by the physicians 5) Dischaged themselves from the hospital based on their own judgement with unknown reasons.

Design outcomes

Primary

MeasureTime frame
1) Number of patients complaining cervical disorders in the self-rated records on the medical interview sheets before and after the physical treatments 2) Pupil light reflex parameters (the initial pupil diameter before the stimulus, the percentage of constriction rate and the velocity of the constriction) before and after the physical treatments

Countries

Japan

Contacts

Public ContactHiroki Fujii

Tokyo Neurological Center Office

fujii@tokyo-neurological-center.com+81-35776-1200

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026