gastric cancer
Conditions
Interventions
None listed
Sponsors
The University of Tokyo
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: <Patients after proximal gastrectomy> 1) Patients who underwent proximal gastrectomy for gastric cancer at the University of Tokyo hospital 2) Patients who are 20-85 years old at the time of consent 3) Patients who do not receive chemotherapy or radiotherapy 4) Patients without recurrence 5) Patients who do not have other malignancy 6) Patients who are not hospitalized 7) Patients with the written consent <Preoperative patients> 1) Patients with gastric cancer who is planed to perform proximal gastrectomy and do not receive neoadjuvant treatment. 2) Patients who are 20-85 years old at the time of consent 3) Patients without other organ malignancy 4) Patients who are not hospitalized 5) Patients with the written consent
Exclusion criteria
Exclusion criteria: 1) Patients within 1 year after proximal gastrectomy (except preoperative patients) 2) Patients who are expected to be difficult to complete the examination 3) Patients who can not suspend anti-acid drugs. 4) Patients who have already joined this trial 5) Patients with contraindication for esophagogastroduodenoscopy. a) hemodynamic and respiratory instability b) hemorrhagic (except anti-coagulant drugs) c) severe anastomotic stenosis d) stenosis or obstruction of the bowel distal to the duodenum e) intolerant to esophagogastroduodenoscopy 6) Patients who have difficulty in swallowing with the catheter inserted 7) Patients with allergy to the drugs we plan to use 8) Patients who are pregnant 9) Patients whom researchers regard as invalid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The difference of internal pressure at the anastomotic site between the types of reconstructions at more than 1 year after proximal gastrectomy. | — |
Secondary
| Measure | Time frame |
|---|---|
| The difference of DeMeester score between the types of reconstructions at more than 1 year after surgery. The change of internal pressure and DeMeester score before and after proximal gastrectomy. The associations between internal pressure or DeMeester score and quality of life. The associations between internal pressure or DeMeester score and body weight change or prognostic nutritional index. | — |
Countries
Japan
Contacts
Public ContactTetsuro Toriumi
Graduate School of Medicine, The University of Tokyo Department of Gastrointestinal Surgery
Outcome results
None listed