N/A (healthy adults)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)Healthy Japanese females aged 20-64 years 2)Those who are sensitive to cold 3)Those whose written informed consent has been obtained
Exclusion criteria
Exclusion criteria: 1)Those who have a history of diabetes, liver disease, kidney disease, digestive system disease, heart disease, or other diseases that may affect the results of this test, or who have had a history of surgery 2)Those with abnormal liver and renal function test values 3)Those who have a disease currently being treated 4)Those with food and drug allergies 5)Those who play intense sports and who are on a diet 6)Those who routinely use internal medicines (including foods and supplements) and skin medicines (applications, patches, sprays, etc.) that are expected to have health-promoting effects on skin tissues and blood / vascular functions 7)Those who cannot stop taking health foods (including foods for specified health use and foods with functional claims) and designated quasi-drugs during the test period 8)Those who continuously take medicines (including OTC and prescription medicines) 9)Those who routinely perform various therapies (esthetic treatment, massage, etc.) that are expected to have health-promoting effects on skin tissue and blood / vascular functions 10)Those with a marked abnormality in the skin condition at the test site or those with chronic skin symptoms such as atopic dermatitis 11)Heavy drinkers, or those who can't stop drinking from the day before the test until the day 12)Those with irregular life patterns and with lifestyle of reversal of day and night 13)Those who have habits of excessive eating and drinking 14)Those who have been pregnant or those who have a plan to become pregnant or breast feed during the study period 15)Those who are participating in or will be participating in other clinical trials at the start of this study, and those within 4 weeks after the end 16)Those who judged that examination responsible doctor is not appropriate for this study participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peripheral blood flow and skin surface temperature | — |
Countries
Japan
Contacts
Ryusendo Co., Ltd. Development Division