Predictors of acute mortality in patients with cardiogenic shock treated with Impella device

Predictors of acute mortality in patients with cardiogenic shock treated with Impella device - Predictors of acute mortality in patients treated with Impella device

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040460

Enrollment

Registered

2020-05-21

Start date

2018-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiogenic shock

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with cardiogenic shock treated with Impella were included. Cardiogenic shock was defined as the presence of all of the following: 1) hypotension (systolic blood pressure < 90 mmHg, or inotropes/vasopressors to maintain systolic blood pressure > 90 mmHg) 2) signs of end organ hypoperfusion (cool extremities, oliguria or anuria, or elevated lactate levels) 3) hemodynamic criteria represented by cardiac index of < 2.2 L/min/m2 or left ventricular end diastolic pressure of > 15 mmHg

Exclusion criteria

Exclusion criteria: Exclusion criteria included the evidence of anoxic brain injury before the implantation, unwitnessed out of hospital cardiac arrest or any cardiac arrest in which ROSC is not achieved in 30 minutes, non-cardiogenic shock (distributive, hypovolemic, or obstructive shock),or severe right ventricular dysfunction.

Design outcomes

Primary

Measure	Time frame
The primary endpoint of this study was defined as all-cause mortality during a 30-day follow-up period after the implantation of Impella device.	—

Secondary

Measure	Time frame
The secondary endpoint was the occurrence of escalated therapy (Impella 5.0 or PCPS) or died.	—

Countries

Japan

Contacts

Public ContactYuhi Fujimoto

Nippon Medical School Hospital Division of cardiovascular medicine

y-fujimoto6081@nms.ac.jp0338222131

Outcome results