head, neck and throat disease, extremities and peripheral vessel disease, disease of the chest wall, abdominal wall and perineum
Conditions
Interventions
The duration of intevention is from obtaining patients'
concent and confirming the eligibility criteria to 30th day after the operation.
The number of intervention is one.
Sponsors
Yamaguchi University Faculty of Medicine and Health Sciences, Yamaguchi University Hospital, the department of Anesthesiology-Resuscitology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients are included if they meet the following eligibility criteria: (1)65 yr old or older; (2)the expected operative duration is from 2 to 8 hours; (3)scheduled head, neck and throat surgery, extremities and peripheral vessel surgery, the chest wall, abdominal wall and perineum surgery.
Exclusion criteria
Exclusion criteria: Patients are excluded if they meet the following exclusion criteria: (1)cerebral parenchyma disease, cerebrovascular disease, myelopathy, peripheral neuropathy, myopathy, mental disorder, dementia; (2)left ventricular ejection fraction is less than 50%, heart valve disease classified moderate or severe; (3)% vital capacity is less than 80%, and/or forced expiratory volume % in 1 second is less than 70%; (4)liver disease classified Child-Pugh B or C; (5)kidney disease with estimated glomerular filtration rate less than 60 mL/min/1.73m2; (6)diabetes mellitus with HbA1c greater than or equal to 8%; (7)body mass index (BMI) is less than 18.5 or greater than or equal to 25.0; (8)scheduled epidural anesthesia and/or peripheral nerve block; (9)emergency operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the duration from discontinuation of the propofol to extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| the incidence of awareness with recall during anesthesia, the incidence of postoperative delirium within 7 days after the operation, and the incidence of myocardial infarction and stroke within 30 days after the operation | — |
Countries
Japan
Contacts
Public ContactShuichi Kaneko
Yamaguchi University Faculty of Medicine and Health Sciences, Yamaguchi University Hospital the department of Anesthesiology-Resuscitology
Outcome results
None listed