Prospective cohort study of thermal balneotherapy in infants

Prospective cohort study of thermal balneotherapy in infants - Prospective cohort study of thermal balneotherapy in infants

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040397

Enrollment

Registered

2020-06-01

Start date

2020-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infant

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Singletons delivered at Beppu Medical Center Neonates born at 37-41 weeks of gestation Birthweight 2500 g or more Apgar score at 5 min 8 or more At least one of the parents with a history of allergic disease

Exclusion criteria

Exclusion criteria: Congenital abnormalities defines as major anomaly in EUROCAT version 2014 Admission to neonatal intensive care unit (NICU)

Design outcomes

Primary

Measure	Time frame
Skin function parameters (transepidermal water loss, stratum corneum hydration, and skin pH) at 5 days, 1 month, 4 months, and 12 months of age.	—

Secondary

Measure	Time frame
The eczema area and severity index (EASI) at 5 days, 1 month, 4 months, and 12 months of age and sensitization to food allergens at 12 months of age.	—

Countries

Japan

Contacts

Public ContactHiroshi Koga

National Hospital Organization Beppu Medical Center Department of Pediatrics

koga.hiroshi.ab@mail.hosp.go.jp+81-977-67-1111

Outcome results