Changes in baroreflex before and after Transcatheter Aortic Valve Implantation. Does autonomic function affect baroreflex recovery?

Changes in baroreflex before and after Transcatheter Aortic Valve Implantation. Does autonomic function affect baroreflex recovery? - Changes in baroreflex before and after Transcatheter Aortic Valve Implantation. Does autonomic function affect baroreflex recovery?

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040391

Enrollment

100

Registered

2020-06-01

Start date

2020-11-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe aortic stenosis

Interventions

Evaluation of autonomic function by heart rate variability analysis Baroreceptor reflex sensitivity measurement by tilt table test

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients diagnosed with aortic stenosis and undergoing transcatheter aortic valve implantation at our hospital over 65 years old Men and women do not matter Mini Cog 3 points or more

Exclusion criteria

Exclusion criteria: Patients with a pacemaker inserted Patients with atrial fibrillation

Design outcomes

Primary

Measure	Time frame
Baroreflex sensitivity (pre operation,post operation,after 1 year)	—

Secondary

Measure	Time frame
All deaths Cardiovascular death All readmissions Cardiovascular readmission Heart rate variability analysis Frailty scale Barthel Index Grip strength, knee extension strength, 4m walking speed Mini-Cog	—

Countries

Japan

Contacts

Public ContactMasahiro Toda

Hamamatsu University School of Medicine,University Hospital Department of Rehabilitation

07485098@hama-med.ac.jp053-435-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026