Elucidation of the pathogenesis of diversion colitis and the usefulness of autologous fecal microbiota transplantation

Elucidation of the pathogenesis of diversion colitis and the usefulness of autologous fecal microbiota - Elucidation of the pathogenesis of diversion colitis and the usefulness of autologous fecal microbiota

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040326

Enrollment

Registered

2020-05-07

Start date

2018-02-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diversion colitis

Interventions

We injected 30-50 mL of saline-diluted autologous feces from the stoma to the diverted colon using a Nelaton catheter

10 FMTs were performed over 4 weeks (every 3 days)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)10 patients who were diagnosed as diversion colitistis in our gastroenterology department after colorectal surgery associated with colorectal cancer or inflammatory bowel disease. The participation is based on the patient's free will. (2) Patients who fully understand this study and can obtain their consent. (3) Patients aged 20 years or older at the time of obtaining consent.

Exclusion criteria

Exclusion criteria: (1) Patients under the age of 20. (2) Pregnant women or nursing patients. (3) Patients within 1 month after bowel surgery. (4) Patients whom doctors deem inappropriate.

Design outcomes

Primary

Measure	Time frame
Elucidate the diverted colon by endoscopy and the change of microbiota 4 weeks after fecal transplantation.	—

Countries

Japan

Contacts

Public ContactKentaro Tominaga

Graduate School of Medical and Dental Sciences, Niigata University Division of Gastroenterology and Hepatology

k-tominaga@med.niigata-u.ac.jp0252272207

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026