Functional MRI study for the association between after sensation and brain functional connectivity network

An fMRI study showing the association between after sensation and brain function - An fMRI study showing the association between after sensation and brain function

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040316

Enrollment

Registered

2020-05-07

Start date

2020-05-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic pain in the orofacial area

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Chronic pain patient group: 1) Right-handed, 2) having chronic orofacial pain for 3 months or more, 3) pain of 4 or more on the Numerical Rating Scale (NRS; scale of 0-10) at the initial visit. Healthy group: 1)Right-handed, 2)age- and sex- matched, 3)not receiving treatment for pain over the past 1 month and more.

Exclusion criteria

Exclusion criteria: Organic brain disease patients MRI Contraindications. Patients who cannot maintain immobility during MRI. Pregnant women or patients who may be pregnant (will). Healthy group only: Mental disorders (depression, epilepsy, schizophrenia, Alzheimer's disease, etc.)

Design outcomes

Primary

Measure	Time frame
Correlation between pain VAS and persistence of after sensation and strength of functional connectivity of brain regions (ACC, IC, PFC, PCC, PAG, thalamus, hypothalamus) in patient groups	—

Countries

Japan

Contacts

Public ContactShizuko Kosugi

Keio University School of Medicine Department of Anesthesiology

shizuko.kosugi@gmail.com03-5363-3810

Outcome results