The efficacy of acute phase intervention in elderly patients with mild trauma on muscle mass maintenance and muscle catabolism biomarker : randomized controlled trial

The efficacy of acute phase intervention in elderly patients with mild trauma on muscle mass maintenance and muscle catabolism biomarker : randomized controlled trial - The efficacy of acute phase intervention in elderly patients with mild trauma on muscle mass maintenance and muscle catabolism biomarker : randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040292

Enrollment

Registered

2020-05-02

Start date

2019-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elderly patients admitted with mild trauma

Interventions

Nutritional supplement containing HMB are given to intervention group twice a day for 14 days, while providing adequate nutrition and early rehabilitation during hospitalization. Nutritional supplemen

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients admitted to the emergency department for trauma with ISS <16 Patients expected to be hospitalized for 3 days or more Patients who have obtained consent from the person or a representative

Exclusion criteria

Exclusion criteria: Non dialysis patients with Cre >3 Patients with anuria Other patients who are determined to be inappropriate as subjects by the principal investigator

Design outcomes

Primary

Measure	Time frame
femoral muscle volume change from day 1 through 14	—

Secondary

Measure	Time frame
Chage of Barthel Index and lower leg circumference from day1 through 14 N-titin level of days 1 and 3	—

Countries

Japan

Contacts

Public ContactHidehiko Hidehiko

Hitachi General Hospital Department of Emergency and Critical Care Medicine

be.rann1988jp@gmail.com0294231111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026