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Prospective observational study evaluating amino acid dynamics during continuous renal replacement therapy

Prospective observational study evaluating amino acid dynamics during continuous renal replacement therapy - Amino acid dynamics in patients receive continuous hemofiltration

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000040283
Enrollment
20
Registered
2020-05-07
Start date
2020-05-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients who undergo continuous hemofiltration

Interventions

None listed

Sponsors

Department of Intensive Care Medicine, Sapporo Medical University School of Medicine
Lead Sponsor
Otsuka Pharmaceutical Factory, Inc.
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients with sepsis or acute kidney injury (KDIGO stage 1 or higher) (2) Patients aged 18 years or older on the date of informed consent (3) Patients who are able to provide written informed consent or whose legally acceptable representative is able to provide written informed consent

Exclusion criteria

Exclusion criteria: (1) Patients with liver failure (2) Patients who need other blood purification therapy within 4 hours after the continuous hemofiltration is started (3) Patients who need to change the conditions of continuous hemofiltration within 4 hours after the continuous hemofiltration is started (4) Patients who need enteral nutrition or parenteral nutrition containing amino acids within 4 hours after the continuous hemofiltration is started (5) Patients who are determined ineligible by the principal investigator

Design outcomes

Primary

MeasureTime frame
Amino acid concentration in the blood Amino acid loss in the filtrate

Secondary

MeasureTime frame
- Thirty-nine amino acid concentrations in the blood - Thirty-nine amino acid concentrations in the filtrate - Urine volume

Countries

Japan

Contacts

Public ContactHiroomi Tatsumi

Sapporo Medical University School of Medicine Department of Intensive Care Medicine

tatsumi@qc4.so-net.ne.jp011-611-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026