Peritoneal dialysis patients
Conditions
Interventions
24-week home-based exercise training, including 20-30 minutes of aerobic exercise thrice-weekly and resistance training twice-weekly. Exercise intensity is determined by the result of major muscle tes
Sponsors
Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, School of Medicine
Department of Nephrology, International University of Health and Welfare, School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Peritoneal dialysis outpatients. 2) Patients from whom written informed consent was obtained.
Exclusion criteria
Exclusion criteria: 1) Patients who are contraindicated for exercise training. Concrete criteria are as follows: patients with uncontrolled persistent hypertension (systolic blood pressure >= 180 mmHg or diastolic pressure >= 110 mmHg); severe anemia (Hb < 7 g/dL); active proliferative diabetic retinopathy; prior symptomatic coronary artery or cerebrovascular diseases within the previous 3 months; uncontrolled heart failure (NYHA >= III); symptomatic or lethal arrhythmia; severe valvular diseases; and walking difficulty due to orthopedic, cerebrovascular and peripheral artery diseases. 2) Unstable PD patients. Concrete criteria are as follows: patients who undergo PD less than 3 months and those with uncontrolled uremia (BUN > 100 mg/dL, K > 6.0 mEq/L and HCO3 < 18 mmoL/L). 3) Patients deemed inadequate for monitoring during study period, as determined by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function assessed by Japanese version of the Montreal Cognitive Assessment, evaluated 24 weeks after assignment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Executive function, aerobic capacity, muscle strength, quality of life, residual renal function and parameters associated with arteriosclerosis, evaluated 24 weeks after assignment. | — |
Countries
Japan
Contacts
Public ContactRyunosuke Mitsuno
Department of internal medicine, Keio University, School of Medicine Division of Endocrinology, Metabolism and Nephrology
Outcome results
None listed