The effect of natural mineral dissolved water on the skin in atopic dermatitis

The effect of natural mineral dissolved water on the skin in atopic dermatitis - The effect of natural mineral dissolved water on the skin in atopic dermatitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000040220

Enrollment

Registered

2020-04-27

Start date

2020-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis

Interventions

Two consecutive weeks of bathing with tap water followed by two consecutive weeks of bathing with natural mineral dissolved water. The patients will visit hospital at days 1, 14 and 28 to measure cl

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Mild atopic dermatitis (EASI socore, less than 16 points) Equal ratio of men to women Outpatient clinic Patients with no change in atopic dermatitis morbidity (no change in topical or medication) in the month prior to the start of the study

Exclusion criteria

Exclusion criteria: Patients who are unable to take bathe for 28 consecutive days during the study Patients with prominent skin erosions and ulcers due to atopic dermatitis

Design outcomes

Primary

Measure	Time frame
Clinical Score (SCORAD, EASI, IGA) at day1, 14 and 28.	—

Secondary

Measure	Time frame
Transepidermal water transpiration and stratum corneum water contentat day 0, 14 and 28. Correlation between clinical scores and transepidermal water transpiration and stratum corneum water content.	—

Countries

Japan

Contacts

Public ContactAkihiko Uchiyama

Gunma University Hospital Department of Dermatology

akihiko1016@gunma-u.ac.jp0272208284

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026