pediatric patients after cardiothoracic surgery
Conditions
Interventions
high flow nasal cannula
conventional oxygen therapy
Sponsors
Department of Anesthesiology and Intensive Care Medicine,Osaka University
Osaka Women'
s and Children'
s Hospital Hyogo Prefectural Kobe Children'
s Hospital Osaka City General Hospital Aichi Children'
s Health and Medical Center National Center for Child Health and Development
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)pediatric patients younger than two years old after cardiothoracic surgery 2)pediatric patients who have been ventilated for more than 12 hours after surgery
Exclusion criteria
Exclusion criteria: 1)patients with tracheostomy 2)patients with DNR(do not resuscitate) 3)patients who have be treated by noninvasive positive pressure ventilation or high flow nasal cannula before surgery 4)patients who undergo unplanned extubation 5)patients who have withdrawn consent from their legal guardian 6)patients who don't need oxygen therapy 7)patients who are planned to receive treatment with noninvasive positive pressure ventilation after extubation 8)patients who are planned to inhale nitric oxide(NO) after extubation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the rate of"escalation of care due to treatment failure" within 72 hours after extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1non event rate within 72 hours after extubation2peripheral oxygen saturation3fractional inspired oxygen4potential of hydrogen5partial pressure of carbon dioxide in arterial blood6respiratory rate7lactate8heart rate9mean blood pressure10catecholamine score11sedative dose12chest x ray score13Inhaled oxygen flow rate14criteria of treatment failure15details of escalation of care16treatment outcome of the patients who have been diagnosed as treatment failure at the time of 72 hours after extubation17the rate of reintubation at the time of 72 hours after extubation18ICU days19hospital days20adverse events21prespecified sub group analysis | — |
Countries
Japan
Contacts
Public ContactTakeshi Yoshida
Osaka University Department of Anesthesiology and Intensive Care Medicine
Outcome results
None listed