Studies on the effects of gut microbiota and bile acid composition on the pathology of liver diseases

Studies on the effects of gut microbiota and bile acid composition on the pathology of liver diseases - Studies on the effects of gut microbiota and bile acid composition on the pathology of liver diseases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000040177

Enrollment

150

Registered

2020-04-18

Start date

2016-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Biliary Cholangitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Liver disease patients (priority to primary biliary cholangitis) Patients with non-liver disease scheduled for endoscopy

Exclusion criteria

Exclusion criteria: Patients who do not agree with the study. Patients who cannot understand the explanation of the study. Patients who cannot undergo colonoscopy due to poor general condition.

Design outcomes

Primary

Measure	Time frame
Diversity of gut microbiome and identification of characteristic bacterial species in patients with primary biliary cholangitis and healthy volunteers	—

Secondary

Measure	Time frame
Fractionation of bile acid composition in the terminal ileum of patients with primary biliary cholangitis and healthy volunteers Expression of bile acid transporter in terminal ileum of patients with primary biliary cholangitis and healthy volunteers	—

Countries

Japan

Contacts

Public ContactShogo Kitahata

Ehime University Graduate School Digestive / Endocrine / Metabolism Internal Medicine

3naika@m.ehime-u.ac.jp089-960-5308

Outcome results