Cocaine-related disorders
Conditions
Interventions
Sequence 1: verum for three weeks, followed by placebo for three weeks. The verum sequence will consist of fifty millesimal potencies (LM2, LM4, and LM6) of Opium and Erythroxylum coca, used for one
Erythroxylum coca: administered in a sucrose globule dissolved on the tongue in the afternoon and evening, plus an extra globule, repeated every hour for six hours, in case of craving). Placebo will c
Sponsors
Brazilian Association of Homeopathic Pharmacists.
HN-Cristiano Homeopatia - Sao Paulo/SP/Brazil https://www.homeopatiahncristiano.com.br/ (Laboratory/Pharmacy) Study medication R$ 13,680 = USD 2,636
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients from a participating Psychosocial Attention Center, in treatment for cocaine use disorder, with a family or other support network.
Exclusion criteria
Exclusion criteria: Remission of cocaine use greater than two weeks; impossibility or unavailability of participating in research in a virtual environment, even with family support.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of days of cocaine use at week 3, recorded by telemedicine using a timeline follow-back methodology. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recorded weekly by telemedicine: The percentage of the reported number of cocaine-using days during participation in the study. Change in participant's cocaine craving measured through the Cocaine Craving Questionnaire scale - brief. Participant's progression assessed by the Clinical Global Impressions Scale. Use of concomitant medications. Occurrence of Adverse Events. Assessment of treatment adherence by the Measure Treatment Adherence scale. Evaluation of participant retention by the number of participants at weeks 3 and 6. Evaluation of study medication use by vial weight at weeks 3 and 6. | — |
Countries
South America
Contacts
Public ContactUbiratan Adler
Sao Carlos Federal University Medicine Department
Outcome results
None listed