Abnormal liver enzymes, hepatitis, NASH, alcohol related liver disease
Conditions
Interventions
One pass 1 actuation (to-and-fro movement) technique was defined as single puncture with a single needle movement into the liver
A 1:3 technique was defined as a single puncture and then 3 to-and-fro
Sponsors
Geisinger Medical Center Department of Gastroenterology and Nutrition
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 18 years of age with elevation of liver biochemistry tests of uncertain etiology, or the need to grade and stage autoimmune, viral, or metabolic liver disease.
Exclusion criteria
Exclusion criteria: Pregnancy Platelet count less than 50,000 per microliter of blood. INR > 1.5 Unable to provide informed consent Ptients who could not discontinue anticoagulation or antiplatelet agents Hemophilia Decompensated liver cirrhosis Those unable to safely undergo the EUS for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint was number of complete portal tracts. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints were sample adequacy for the pathologic diagnosis, length of longest piece, aggregate specimen length, and adverse events. | — |
Countries
North America
Contacts
Public ContactKelly Haddock
Geisinger Medical Center Department of Gastroenterology and Nutrition
Outcome results
None listed