Epilepsy, Parkinson'
Conditions
Interventions
Participants: Patients with epilepsy implanted with chronic subdural or depth electrodes for epileptogenic focus surgery. Duration: 2 ~ 4 weeks (1~3 hours / day) Study: Measuring neural activities
Sponsors
Jichi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. In a good condition after the surgery. 2. Obtained informed consent from the patient 3. Patients whose ages are more than 8 years old.
Exclusion criteria
Exclusion criteria: 1. When the patient seems unfit to participate in the study such as restlessness and disturbance of consciousness. 2. a pacemaker is implanted. 3. the metal is in the body for use in surgery or drug injection. 4. there is a possibility that a piece of metal has been accidentally introduced into the body from working in the metal processing industry. 5. Claustrophobia; 6. Severe shortness of breath when lying down.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The neural activities during cognitive tasks and the behavioral performances of the cognitive tasks by stimulation of the cortex will be evaluated. The evaluation will be performed before epileptogenic focus resection surgery (~4 weeks). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The neural activities during cognitive tasks and the behavioral performances of the cognitive tasks by stimulation of subcortical areas will be evaluated. The evaluation will be performed before the implantation of the stimulation device used in deep brain stimulation therapy (~2 week). 2. In patients undergoing epileptic focal resection, device implantation for deep brain stimulation therapy, brain tumors, or cerebrovascular disease surgery, functional magnetic resonance imaging are used to assess the activity of cortical and subcortical areas during cognitive tasks and at rest. Evaluations will be performed before the surgery, and 1 month and 6 month after the surgery. | — |
Countries
Japan
Contacts
Public ContactKensuke Kawai
Jichi Medical University Department of Neurosurgery
Outcome results
None listed