Healthy adult male and female
Conditions
Interventions
Intake of the low dose of prebiotics material + polymer material dose1, once a day for 2 weeks
Intake of the low dose of prebiotics material + polymer material dose2, once a day for 2 weeks
Intake of
Sponsors
KSO Corporation
KSO Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Japanese healthy male and female aged 20-60 years whose defecation frequency is 3-5 times a week (2)Subjects who have low-level Bifidobacterium at the point of screening (3)Subjects who usually take three meals a day (4)Subjects who have received a sufficient explanation of the purpose and contents of the examination, have the ability to consent, have well understood, volunteered to participate, and have signed the informed consent document
Exclusion criteria
Exclusion criteria: (1)Subjects who usually take intestinal drugs and laxatives (2)Subjects who cannot stop the consumption of healthy foods which may have good effect on constipation during the test period (3)Subjects who usually take healthy supplements (4)Subjects who cannot stop the consumption of foods which are containing lactic acid bacteria, bifidobacteria, oligosaccharides, and natto bacteria (probiotics and prebiotics materials ) (5)Subjects who have gastrointestinal disorders or a surgical history and who usually take gastrointestinal drugs (6)Subjects who have been diagnosed irritable bowel syndrome or inflammatory bowel disease (7)Subjects who have liver disease, kidney disease and diabetes mellitus (8)Subjects who have allergic to food (9)Subjects who have pollinosis and take drugs which affects gut microbiome (10)Subjects who are pregnant or breast-feeding, or planning to be pregnant during the test period (11)Subjects who participate in other clinical trials (food, pharmaceuticals and cosmetics), who have participated in other tests within one month of obtaining consent, or who are willing to participate (12)Subjects who are judged as unsuitable for the study by the investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composition ratio of gut microbiome | — |
Secondary
| Measure | Time frame |
|---|---|
| -Defecation status -Gastrointestinal condition and appetite -Mood status -Skin condition and sleep quality | — |
Countries
Japan
Contacts
Public ContactKentaro Umeda
Ajinomoto Co., Inc. Institute of Food Sciences and Technologies
Outcome results
None listed